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Na(+) Block and Permeation in a K(+) Channel of Known Structure
The effects of intracellular Na(+) were studied on K(+) and Rb(+) currents through single KcsA channels. At low voltage, Na(+) produces voltage-dependent block, which becomes relieved at high voltage by a “punchthrough” mechanism representing Na(+) escaping from its blocking site through the selecti...
Autores principales: | Nimigean, Crina M., Miller, Christopher |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229518/ https://www.ncbi.nlm.nih.gov/pubmed/12198089 http://dx.doi.org/10.1085/jgp.20028614 |
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