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Na(+) Block and Permeation in a K(+) Channel of Known Structure

The effects of intracellular Na(+) were studied on K(+) and Rb(+) currents through single KcsA channels. At low voltage, Na(+) produces voltage-dependent block, which becomes relieved at high voltage by a “punchthrough” mechanism representing Na(+) escaping from its blocking site through the selecti...

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Detalles Bibliográficos
Autores principales: Nimigean, Crina M., Miller, Christopher
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229518/
https://www.ncbi.nlm.nih.gov/pubmed/12198089
http://dx.doi.org/10.1085/jgp.20028614

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