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The Role of NH(2)-terminal Positive Charges in the Activity of Inward Rectifier K(ATP) Channels

Approximately half of the NH(2) terminus of inward rectifier (Kir) channels can be deleted without significant change in channel function, but activity is lost when more than ∼30 conserved residues before the first membrane spanning domain (M1) are removed. Systematic replacement of the positive cha...

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Detalles Bibliográficos
Autores principales:	Cukras, C.A., Jeliazkova, I., Nichols, C.G.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229524/ https://www.ncbi.nlm.nih.gov/pubmed/12198096 http://dx.doi.org/10.1085/jgp.20028621

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