Cargando…
Side-chain Charge Effects and Conductance Determinants in the Pore of ClC-0 Chloride Channels
The charge on the side chain of the internal pore residue lysine 519 (K519) of the Torpedo ClC-0 chloride (Cl(−)) channel affects channel conductance. Experiments that replace wild-type (WT) lysine with neutral or negatively charged residues or that modify the K519C mutant with various methane thios...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2003
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229543/ https://www.ncbi.nlm.nih.gov/pubmed/12885875 http://dx.doi.org/10.1085/jgp.200308844 |