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Side-chain Charge Effects and Conductance Determinants in the Pore of ClC-0 Chloride Channels

The charge on the side chain of the internal pore residue lysine 519 (K519) of the Torpedo ClC-0 chloride (Cl(−)) channel affects channel conductance. Experiments that replace wild-type (WT) lysine with neutral or negatively charged residues or that modify the K519C mutant with various methane thios...

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Detalles Bibliográficos
Autores principales:	Chen, Mei-Fang, Chen, Tsung-Yu
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2003
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229543/ https://www.ncbi.nlm.nih.gov/pubmed/12885875 http://dx.doi.org/10.1085/jgp.200308844

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