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Regulation of AE2-mediated Cl(−) Transport by Intracellular or by Extracellular pH Requires Highly Conserved Amino Acid Residues of the AE2 NH(2)-terminal Cytoplasmic Domain

We reported recently that regulation by intracellular pH (pH(i)) of the murine Cl(−)/HCO(3) (−) exchanger AE2 requires amino acid residues 310–347 of the polypeptide's NH(2)-terminal cytoplasmic domain. We have now identified individual amino acid residues within this region whose integrity is...

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Detalles Bibliográficos
Autores principales: Stewart, A.K., Chernova, M.N., Shmukler, B.E., Wilhelm, S., Alper, S.L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2002
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229549/
https://www.ncbi.nlm.nih.gov/pubmed/12407081
http://dx.doi.org/10.1085/jgp.20028641