A protein knockdown strategy to study the function of β-catenin in tumorigenesis

BACKGROUND: The Wnt signaling pathway plays critical roles in cell proliferation and cell fate determination at many stages of development. A critical downstream target of Wnt signaling is the cytosolic β-catenin, which is stabilized upon Wnt activation and promotes transcription of a variety of tar...

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Detalles Bibliográficos
Autores principales: Cong, Feng, Zhang, Jianxuan, Pao, William, Zhou, Pengbo, Varmus, Harold
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC222962/
https://www.ncbi.nlm.nih.gov/pubmed/14516475
http://dx.doi.org/10.1186/1471-2199-4-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC222962/
https://www.ncbi.nlm.nih.gov/pubmed/14516475
http://dx.doi.org/10.1186/1471-2199-4-10

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