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A protein knockdown strategy to study the function of β-catenin in tumorigenesis
BACKGROUND: The Wnt signaling pathway plays critical roles in cell proliferation and cell fate determination at many stages of development. A critical downstream target of Wnt signaling is the cytosolic β-catenin, which is stabilized upon Wnt activation and promotes transcription of a variety of tar...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2003
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC222962/ https://www.ncbi.nlm.nih.gov/pubmed/14516475 http://dx.doi.org/10.1186/1471-2199-4-10 |