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Can Shaker Potassium Channels be Locked in the Deactivated State?

For structural studies it would be useful to constrain the voltage sensor of a voltage-gated channel in its deactivated state. Here we consider one Shaker potassium channel mutant and speculate about others that might allow the channel to remain deactivated at zero membrane potential. Ionic and gati...

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Detalles Bibliográficos
Autores principales:	Yang, Youshan, Yan, Yangyang, Sigworth, Fred J.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2004
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229620/ https://www.ncbi.nlm.nih.gov/pubmed/15277577 http://dx.doi.org/10.1085/jgp.200409057

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