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Plasma membrane expression of GnRH receptors: regulation by antagonists in breast, prostate, and gonadotrope cell lines

In heterologous expression systems, human GnRH receptors (hGnRHRs) are poorly expressed at the cell surface and this may reflect inefficient exit from the endoplasmic reticulum. Here, we have defined the proportion of GnRHRs at the cell surface using a novel assay based on adenoviral transduction wi...

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Detalles Bibliográficos
Autores principales: Finch, Ann R, Sedgley, Kathleen R, Caunt, Christopher J, McArdle, Craig A
Formato: Texto
Lenguaje:English
Publicado: BioScientifica 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229628/
https://www.ncbi.nlm.nih.gov/pubmed/18252959
http://dx.doi.org/10.1677/JOE-07-0471