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On the Molecular Basis of Ion Permeation in the Epithelial Na(+) Channel
The epithelial Na(+) channel (ENaC) is highly selective for Na(+) and Li(+) over K(+) and is blocked by the diuretic amiloride. ENaC is a heterotetramer made of two α, one β, and one γ homologous subunits, each subunit comprising two transmembrane segments. Amino acid residues involved in binding of...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229642/ https://www.ncbi.nlm.nih.gov/pubmed/10398689 |