MAO-B Elevation in Mouse Brain Astrocytes Results in Parkinson's Pathology

Age-related increases in monoamine oxidase B (MAO-B) may contribute to neurodegeneration associated with Parkinson's disease (PD). The MAO-B inhibitor deprenyl, a long-standing antiparkinsonian therapy, is currently used clinically in concert with the dopamine precursor L-DOPA. Clinical studies...

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Detalles Bibliográficos
Autores principales: Mallajosyula, Jyothi K., Kaur, Deepinder, Chinta, Shankar J., Rajagopalan, Subramanian, Rane, Anand, Nicholls, David G., Di Monte, Donato A., Macarthur, Heather, Andersen, Julie K.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229649/
https://www.ncbi.nlm.nih.gov/pubmed/18286173
http://dx.doi.org/10.1371/journal.pone.0001616

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