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Sulfadoxine-Pyrimethamine–Based Combinations for Malaria: A Randomised Blinded Trial to Compare Efficacy, Safety and Selection of Resistance in Malawi
BACKGROUND: In Malawi, there has been a return of Plasmodium falciparum sensitivity to chloroquine (CQ) since sulfadoxine-pyrimethamine (SP) replaced CQ as first line treatment for uncomplicated malaria. When used for prophylaxis, Amodiaquine (AQ) was associated with agranulocytosis but is considere...
Autores principales: | Bell, David J., Nyirongo, Suzgo K., Mukaka, Mavuto, Zijlstra, Ed E., Plowe, Christopher V., Molyneux, Malcolm E., Ward, Steve A., Winstanley, Peter A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229666/ https://www.ncbi.nlm.nih.gov/pubmed/18270569 http://dx.doi.org/10.1371/journal.pone.0001578 |
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