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Novel mutations in ribosomal proteins L4 and L22 that confer erythromycin resistance in Escherichia coli

L4 and L22, proteins of the large ribosomal subunit, contain globular surface domains and elongated ‘tentacles’ that reach into the core of the large subunit to form part of the lining of the peptide exit tunnel. Mutations in the tentacles of L4 and L22 confer macrolide resistance in a variety of pa...

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Detalles Bibliográficos
Autores principales: Zaman, Sephorah, Fitzpatrick, Megan, Lindahl, Lasse, Zengel, Janice
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229831/
https://www.ncbi.nlm.nih.gov/pubmed/17956547
http://dx.doi.org/10.1111/j.1365-2958.2007.05975.x