Mutation of RNA Pol III Subunit rpc2/polr3b Leads to Deficiency of Subunit Rpc11 and Disrupts Zebrafish Digestive Development

The role of RNA polymerase III (Pol III) in developing vertebrates has not been examined. Here, we identify a causative mutation of the second largest Pol III subunit, polr3b, that disrupts digestive organ development in zebrafish slim jim (slj) mutants. The slj mutation is a splice-site substitutio...

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Detalles Bibliográficos
Autores principales: Yee, Nelson S, Gong, Weilong, Huang, Ying, Lorent, Kristin, Dolan, Amy C, Maraia, Richard J, Pack, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2229849/
https://www.ncbi.nlm.nih.gov/pubmed/18044988
http://dx.doi.org/10.1371/journal.pbio.0050312

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