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PACAP-38 induces neuronal differentiation of human SH-SY5Y neuroblastoma cells via cAMP-mediated activation of ERK and p38 MAP kinases1

The intracellular signaling pathways mediating the neurotrophic actions of pituitary adenylate cyclase-activating polypeptide (PACAP) were investigated in human neuroblastoma SH-SY5Y cells. Previously, we showed that SH-SY5Y cells express the PAC(1) and VIP/PACAP receptor type 2 (VPAC(2)) receptors,...

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Detalles Bibliográficos
Autores principales: Monaghan, T K, MacKenzie, C J, Plevin, R, Lutz, E M
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230095/
https://www.ncbi.nlm.nih.gov/pubmed/17995938
http://dx.doi.org/10.1111/j.1471-4159.2007.05018.x