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Cysteine Modification of a Putative Pore Residue in Clc-0: Implication for the Pore Stoichiometry of Clc Chloride Channels

The ClC channel family consists of chloride channels important for various physiological functions. Two members in this family, ClC-0 and ClC-1, share ∼50–60% amino acid identity and show similar gating behaviors. Although they both contain two subunits, the number of pores present in the homodimeri...

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Detalles Bibliográficos
Autores principales: Lin, Chia-Wei, Chen, Tsung-Yu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230621/
https://www.ncbi.nlm.nih.gov/pubmed/11004203

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