Cargando…
Cysteine Modification of a Putative Pore Residue in Clc-0: Implication for the Pore Stoichiometry of Clc Chloride Channels
The ClC channel family consists of chloride channels important for various physiological functions. Two members in this family, ClC-0 and ClC-1, share ∼50–60% amino acid identity and show similar gating behaviors. Although they both contain two subunits, the number of pores present in the homodimeri...
Autores principales: | Lin, Chia-Wei, Chen, Tsung-Yu |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230621/ https://www.ncbi.nlm.nih.gov/pubmed/11004203 |
Ejemplares similares
-
Side-chain Charge Effects and Conductance Determinants in the Pore of ClC-0 Chloride Channels
por: Chen, Mei-Fang, et al.
Publicado: (2003) -
Conformational Changes in the Pore of CLC-0
por: Accardi, Alessio, et al.
Publicado: (2003) -
Gating the glutamate gate of CLC-2 chloride channel by pore occupancy
por: De Jesús-Pérez, José J., et al.
Publicado: (2016) -
Probing the Pore of ClC-0 by Substituted Cysteine Accessibility Method Using Methane Thiosulfonate Reagents
por: Lin, Chia-Wei, et al.
Publicado: (2003) -
Blocking Pore-open Mutants of CLC-0 by Amphiphilic Blockers
por: Zhang, Xiao-Dong, et al.
Publicado: (2009)