Cargando…

Phosphoinositides Decrease Atp Sensitivity of the Cardiac Atp-Sensitive K(+) Channel: A Molecular Probe for the Mechanism of Atp-Sensitive Inhibition

Anionic phospholipids modulate the activity of inwardly rectifying potassium channels (Fan, Z., and J.C. Makielski. 1997. J. Biol. Chem. 272:5388–5395). The effect of phosphoinositides on adenosine triphosphate (ATP) inhibition of ATP-sensitive potassium channel (K(ATP)) currents was investigated us...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Zheng, Makielski, Jonathan C.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1999
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230641/ https://www.ncbi.nlm.nih.gov/pubmed/10436001

Ejemplares similares

Molecular Analysis of ATP-sensitive K Channel Gating and Implications for Channel Inhibition by ATP
por: Trapp, Stefan, et al.
Publicado: (1998)

Surface charge and properties of cardiac ATP-sensitive K+ channels
Publicado: (1994)

Mechanism of ATP-sensitive K Channel Inhibition by Sulfhydryl Modification
por: Trapp, Stefan, et al.
Publicado: (1998)

Mice expressing a human K(ATP) channel mutation have altered channel ATP sensitivity but no cardiac abnormalities
por: Clark, R., et al.
Publicado: (2012)

Cardiac ATP-sensitive K+ channels. Evidence for preferential regulation by glycolysis
Publicado: (1989)

ATP-sensitive potassium channel (K(ATP )channel) expression in the normal canine pancreas and in canine insulinomas
por: Donley, Vicky R, et al.
Publicado: (2005)

Increase of ATP-sensitive potassium (K(ATP)) channels in the heart of type-1 diabetic rats
por: Chen, Zhih-Cherng, et al.
Publicado: (2012)

The ATP sensitive potassium channel (K(ATP)) is a novel target for migraine drug development
por: Clement, Amalie, et al.
Publicado: (2023)

Ligand-insensitive State of Cardiac ATP-sensitive K(+) Channels : Basis for Channel Opening
por: Alekseev, Alexey E., et al.
Publicado: (1998)

Modulatory Effect of Medicinal Plants and Their Active Constituents on ATP-Sensitive Potassium Channels (K(ATP)) in Diabetes
por: Al Kury, Lina T.
Publicado: (2023)

Block of cardiac ATP-sensitive K+ channels by external divalent cations is modulated by intracellular ATP. Evidence for allosteric regulation of the channel protein
Publicado: (1993)

Localization of ATP-sensitive K(+) channel subunits in rat liver
por: Zhou, Ming, et al.
Publicado: (2019)

Targeting ATP-Sensitive K(+) Channels to Treat Pulmonary Hypertension
por: Breen, Ellen, et al.
Publicado: (2022)

How ATP Inhibits the Open K(ATP) Channel
por: Craig, Tim J., et al.
Publicado: (2008)

Endothelial biology and ATP-sensitive potassium channels
por: Aziz, Qadeer, et al.
Publicado: (2018)

Identification of an ATP-sensitive potassium channel in mitochondria
por: Paggio, Angela, et al.
Publicado: (2019)

Engineered interaction between SUR1 and Kir6.2 that enhances ATP sensitivity in K(ATP) channels
por: Pratt, Emily B., et al.
Publicado: (2012)

The α-Cell Conundrum: ATP-Sensitive K(+) Channels and Glucose Sensing
por: Jacobson, David A., et al.
Publicado: (2009)

Nucleotide inhibition of the pancreatic ATP-sensitive K(+) channel explored with patch-clamp fluorometry
por: Usher, Samuel G, et al.
Publicado: (2020)

Natriuretic peptides modulate ATP-sensitive K(+) channels in rat ventricular cardiomyocytes
por: Burley, Dwaine S., et al.
Publicado: (2014)

Physiological function and molecular composition of ATP-sensitive K(+) channels in human gastric smooth muscle
por: Lee, Sang Eok, et al.
Publicado: (2020)

Functional protection against cardiac diseases depends on ATP‐sensitive potassium channels
por: Ye, Peng, et al.
Publicado: (2018)

Expression of ATP-sensitive potassium channels in human pregnant myometrium
por: Xu, Chen, et al.
Publicado: (2011)

Pharmacological rescue of trafficking-impaired ATP-sensitive potassium channels
por: Martin, Gregory M., et al.
Publicado: (2013)

Ocular Hypotensive Properties and Biochemical Profile of QLS-101, a Novel ATP-Sensitive Potassium (K(ATP)) Channel Opening Prodrug
por: Pervan-Steel, Cynthia L., et al.
Publicado: (2022)

Activation mechanism of ATP-sensitive K(+) channels explored with real-time nucleotide binding
por: Puljung, Michael, et al.
Publicado: (2019)

Overactive ATP-Sensitive K(+) Channels Compromise Lymphatic Contractile Function in Cantú Syndrome
por: Aziz, Qadeer
Publicado: (2023)

Cytomembrane ATP-sensitive K(+) channels in neurovascular unit targets of ischemic stroke in the recovery period
por: Zhang, Yang, et al.
Publicado: (2016)

Open State Destabilization by Atp Occupancy Is Mechanism Speeding Burst Exit Underlying K(ATP) Channel Inhibition by Atp
por: Li, Lehong, et al.
Publicado: (2002)

Vasoconstrictors inhibit ATP-sensitive K+ channels in arterial smooth muscle through protein kinase C
Publicado: (1996)

Loss of ATP-sensitive channel expression and function decreases opioid sensitivity in a mouse model of type 2 diabetes
por: Fisher, Cole, et al.
Publicado: (2023)

Coexpression of the Type 2 Diabetes Susceptibility Gene Variants KCNJ11 E23K and ABCC8 S1369A Alter the ATP and Sulfonylurea Sensitivities of the ATP-Sensitive K(+) Channel
por: Hamming, Kevin S.C., et al.
Publicado: (2009)

Ligand-dependent Linkage of the ATP Site to Inhibition Gate Closure in the K(ATP) Channel
por: Li, Lehong, et al.
Publicado: (2005)

Regulation of myometrial contraction by ATP-sensitive potassium (K(ATP)) channel via activation of SUR2B and Kir 6.2 in mouse
por: HONG, Seung Hwa, et al.
Publicado: (2016)

ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway
por: Roy Chowdhury, Uttio, et al.
Publicado: (2017)

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity
por: Fatehi, Mohammad, et al.
Publicado: (2015)

Reduced dihydroxyacetone sensitivity and normal sensitivity to glyceraldehyde and oxidizing agent of ATP-sensitive K+ channels of pancreatic beta cells in NIDDM rats.
por: Song, D. K., et al.
Publicado: (1997)

Evidence for the Participation of ATP-sensitive Potassium Channels in the Antinociceptive Effect of Curcumin
por: De Paz-Campos, Marco Antonio, et al.
Publicado: (2012)

Role of ATP-sensitive potassium channels on hypoxic pulmonary vasoconstriction in endotoxemia
por: Turzo, Maurizio, et al.
Publicado: (2018)

ATP-Sensitive Potassium Channels in Migraine: Translational Findings and Therapeutic Potential
por: Clement, Amalie, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_qmuurcos51e7gk966tf432bvoi