Cystic Fibrosis Transmembrane Conductance Regulator: Physical Basis for Lyotropic Anion Selectivity Patterns

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl channel exhibits lyotropic anion selectivity. Anions that are more readily dehydrated than Cl exhibit permeability ratios (P (S)/P (Cl)) greater than unity and also bind more tightly in the channel. We compared the selectivity of CFTR...

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Detalles Bibliográficos
Autores principales: Smith, Stephen S., Steinle, Erich D., Meyerhoff, Mark E., Dawson, David C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230651/
https://www.ncbi.nlm.nih.gov/pubmed/10578016

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