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Operating Regimes of Signaling Cycles: Statics, Dynamics, and Noise Filtering
A ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades). Our paper explores the kind of information processing and filtering that can be accomplished by this simple biochemical circuit. Signaling cycles are...
Autores principales: | Gomez-Uribe, Carlos, Verghese, George C, Mirny, Leonid A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2230677/ https://www.ncbi.nlm.nih.gov/pubmed/18159939 http://dx.doi.org/10.1371/journal.pcbi.0030246 |
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