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Amyloid precursor protein modulates β-catenin degradation

BACKGROUND: The amyloid precursor protein (APP) is genetically associated with Alzheimer's disease (AD). Elucidating the function of APP should help understand AD pathogenesis and provide insights into therapeutic designs against this devastating neurodegenerative disease. RESULTS: We demonstra...

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Detalles Bibliográficos
Autores principales: Chen, Yuzhi, Bodles, Angela M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231348/
https://www.ncbi.nlm.nih.gov/pubmed/18070361
http://dx.doi.org/10.1186/1742-2094-4-29