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Amyloid precursor protein modulates β-catenin degradation
BACKGROUND: The amyloid precursor protein (APP) is genetically associated with Alzheimer's disease (AD). Elucidating the function of APP should help understand AD pathogenesis and provide insights into therapeutic designs against this devastating neurodegenerative disease. RESULTS: We demonstra...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2007
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231348/ https://www.ncbi.nlm.nih.gov/pubmed/18070361 http://dx.doi.org/10.1186/1742-2094-4-29 |