Generalizing Terwilliger's likelihood approach: a new score statistic to test for genetic association

BACKGROUND: In this paper, we propose a one degree of freedom test for association between a candidate gene and a binary trait. This method is a generalization of Terwilliger's likelihood ratio statistic and is especially powerful for the situation of one associated haplotype. As an alternative...

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Detalles Bibliográficos
Autores principales: el Galta, Rachid, Uitte de Willige, Shirley, de Visser, Marieke CH, Helmer, Quinta, Hsu, Li, Houwing-Duistermaat, Jeanine J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231383/
https://www.ncbi.nlm.nih.gov/pubmed/17892585
http://dx.doi.org/10.1186/1471-2156-8-63

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231383/
https://www.ncbi.nlm.nih.gov/pubmed/17892585
http://dx.doi.org/10.1186/1471-2156-8-63

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