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Generalizing Terwilliger's likelihood approach: a new score statistic to test for genetic association
BACKGROUND: In this paper, we propose a one degree of freedom test for association between a candidate gene and a binary trait. This method is a generalization of Terwilliger's likelihood ratio statistic and is especially powerful for the situation of one associated haplotype. As an alternative...
Autores principales: | el Galta, Rachid, Uitte de Willige, Shirley, de Visser, Marieke CH, Helmer, Quinta, Hsu, Li, Houwing-Duistermaat, Jeanine J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231383/ https://www.ncbi.nlm.nih.gov/pubmed/17892585 http://dx.doi.org/10.1186/1471-2156-8-63 |
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