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Gating Induces a Conformational Change in the Outer Vestibule of Enac
The epithelial Na(+) channel (ENaC) is comprised of three homologous subunits (α, β, and γ). The channel forms the pathway for Na(+) absorption in the kidney, and mutations cause disorders of Na(+) homeostasis. However, little is known about the mechanisms that control the gating of ENaC. We investi...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231819/ https://www.ncbi.nlm.nih.gov/pubmed/11099347 |