Mutation of a Single Residue in the S2–S3 Loop of Cng Channels Alters the Gating Properties and Sensitivity to Inhibitors

We previously found that native cyclic nucleotide–gated (CNG) cation channels from amphibian rod cells are directly and reversibly inhibited by analogues of diacylglycerol (DAG), but little is known about the mechanism of this inhibition. We recently determined that, at saturating cGMP concentration...

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Detalles Bibliográficos
Autores principales: Crary, Jennifer I., Dean, Dylan M., Maroof, Farahnaz, Zimmerman, Anita L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2000
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2231820/
https://www.ncbi.nlm.nih.gov/pubmed/11099346

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