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Mechanism of Irk1 Channel Block by Intracellular Polyamines
Intracellular polyamines inhibit the strongly rectifying IRK1 potassium channel by a mechanism different from that of a typical ionic pore blocker such as tetraethylammonium. As in other K(+) channels, in the presence of intracellular TEA, the IRK1 channel current decreases with increasing membrane...
Autores principales: | Guo, Donglin, Lu, Zhe |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2232894/ https://www.ncbi.nlm.nih.gov/pubmed/10828252 |
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