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Dynamic and redundant regulation of LRRK2 and LRRK1 expression

BACKGROUND: Mutations within the leucine-rich repeat kinase 2 (LRRK2) gene account for a significant proportion of autosomal-dominant and some late-onset sporadic Parkinson's disease. Elucidation of LRRK2 protein function in health and disease provides an opportunity for deciphering molecular p...

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Detalles Bibliográficos
Autores principales:	Biskup, Saskia, Moore, Darren J, Rea, Alexis, Lorenz-Deperieux, Bettina, Coombes, Candice E, Dawson, Valina L, Dawson, Ted M, West, Andrew B
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233633/ https://www.ncbi.nlm.nih.gov/pubmed/18045479 http://dx.doi.org/10.1186/1471-2202-8-102

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