Cargando…

Selective Open-Channel Block of Shaker (Kv1) Potassium Channels by S-Nitrosodithiothreitol (Sndtt)

Large quaternary ammonium (QA) ions block voltage-gated K(+) (Kv) channels by binding with a 1:1 stoichiometry in an aqueous cavity that is exposed to the cytoplasm only when channels are open. S-nitrosodithiothreitol (SNDTT; ONSCH(2)CH(OH)CH(OH)CH(2)SNO) produces qualitatively similar “open-channel...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brock, Mathew W., Mathes, Chris, Gilly, William F.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2001
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233744/ https://www.ncbi.nlm.nih.gov/pubmed/11429448

Ejemplares similares

Constitutive Activation of the Shaker Kv Channel
por: Sukhareva, Manana, et al.
Publicado: (2003)

Open channel block of Kv1.4 potassium channels by aripiprazole
por: Park, Jeaneun, et al.
Publicado: (2020)

Regulating Shaker Kv channel clustering by hetero-oligomerization
por: Nsasra, Esraa, et al.
Publicado: (2023)

Selectivity Changes during Activation of Mutant Shaker Potassium Channels
por: Zheng, Jie, et al.
Publicado: (1997)

Shaker potassium channel gating. I: Transitions near the open state
Publicado: (1994)

Position and motions of the S4 helix during opening of the Shaker potassium channel
por: Phillips, L. Revell, et al.
Publicado: (2010)

Electrostatics and the Gating Pore of Shaker Potassium Channels
por: Islas, Leon D., et al.
Publicado: (2001)

External barium block of Shaker potassium channels: evidence for two binding sites
Publicado: (1995)

Structure of the Shaker Kv channel and mechanism of slow C-type inactivation
por: Tan, Xiao-Feng, et al.
Publicado: (2022)

Can Shaker Potassium Channels be Locked in the Deactivated State?
por: Yang, Youshan, et al.
Publicado: (2004)

Investigating the Putative Glycine Hinge in Shaker Potassium Channel
por: Ding, Shinghua, et al.
Publicado: (2005)

Opening the Shaker K(+) channel with hanatoxin
por: Milescu, Mirela, et al.
Publicado: (2013)

How Does the W434F Mutation Block Current in Shaker Potassium Channels?
por: Yang, Youshan, et al.
Publicado: (1997)

Activation of Shaker Potassium Channels : II. Kinetics of the V2 Mutant Channel
por: Schoppa, N.E., et al.
Publicado: (1998)

Antidepressant drug paroxetine blocks the open pore of Kv3.1 potassium channel
por: Lee, Hyang Mi, et al.
Publicado: (2018)

The antidiabetic drug rosiglitazone blocks Kv1.5 potassium channels in an open state
por: Lee, Hyang Mi, et al.
Publicado: (2022)

A Gastropod Toxin Selectively Slows Early Transitions in the Shaker K Channel's Activation Pathway
por: Sack, Jon T., et al.
Publicado: (2004)

Flow and shortcuts along the Shaker Kv channel slow inactivation gating cycle
por: Nirenberg, Valerie Abigail, et al.
Publicado: (2020)

Intermediate Conductances during Deactivation of Heteromultimeric Shaker Potassium Channels
por: Zheng, Jie, et al.
Publicado: (1998)

Regulated RNA Editing and Functional Epistasis in Shaker Potassium Channels
por: Ingleby, Lindsey, et al.
Publicado: (2009)

Topology of the Shaker Potassium Channel Probed with Hydrophilic Epitope Insertions
por: Shih, Theodore M., et al.
Publicado: (1997)

Probing the Cavity of the Slow Inactivated Conformation of Shaker Potassium Channels
por: Panyi, Gyorgy, et al.
Publicado: (2007)

Shaker potassium channel gating. II: Transitions in the activation pathway
Publicado: (1994)

Role of the S3-S4 Linker in Shaker Potassium Channel Activation
por: Mathur, Rajesh, et al.
Publicado: (1997)

Mechanisms Underlying C-type Inactivation in Kv Channels: Lessons From Structures of Human Kv1.3 and Fly Shaker-IR Channels
por: Ong, Seow Theng, et al.
Publicado: (2022)

Open channel block of Kv1.5 channels by HMQ1611
por: Dong, Chao, et al.
Publicado: (2022)

Energetics of Shaker K channels block by inactivation peptides
Publicado: (1993)

Determinants of Voltage-Dependent Gating and Open-State Stability in the S5 Segment of Shaker Potassium Channels
por: Kanevsky, Max, et al.
Publicado: (1999)

Voltage Sensitivity and Gating Charge in Shaker and Shab Family Potassium Channels
por: Islas, Leon D., et al.
Publicado: (1999)

Tail End of the S6 Segment: Role in Permeation in Shaker Potassium Channels
por: Ding, Shinghua, et al.
Publicado: (2002)

Shaker potassium channel gating. III: Evaluation of kinetic models for activation
Publicado: (1994)

Activation of Shaker Potassium Channels : I. Characterization of Voltage-dependent Transitions
por: Schoppa, N.E., et al.
Publicado: (1998)

Charge-voltage curves of Shaker potassium channel are not hysteretic at steady state
por: Cowgill, John, et al.
Publicado: (2023)

Ion Channel Modeling beyond State of the Art: A Comparison with a System Theory-Based Model of the Shaker-Related Voltage-Gated Potassium Channel Kv1.1
por: Langthaler, Sonja, et al.
Publicado: (2022)

The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel
por: Zhao, Juan, et al.
Publicado: (2016)

Cross Talk between Activation and Slow Inactivation Gates of Shaker Potassium Channels
por: Panyi, Gyorgy, et al.
Publicado: (2006)

Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle
Publicado: (1990)

On the role of ball and chain interactions in recovery from the inactivation of the shaker potassium channel
por: Borys, Przemysław, et al.
Publicado: (2008)

The Shaker Type Potassium Channel, GORK, Regulates Abscisic Acid Signaling in Arabidopsis
por: Lim, Chae Woo, et al.
Publicado: (2019)

Correction: Charge-voltage curves of Shaker potassium channel are not hysteretic at steady state
por: Cowgill, John, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_f493nghaccrmncv4q33t4qrkgc