The Progress on Genetic Analysis of Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is one of the most common cancers in Southeast Asia. Both genetic and environmental factors contribute to the tumorigenesis of NPC, most notably the consumption of certain salted food items and Epstein-Barr virus inf...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaofeng, Cui, Jing, Macias, Virgilia, Kajdacsy-Balla, André A., Ye, Hui, Wang, Jianguang, Rao, P. Nagesh
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2007
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233780/
https://www.ncbi.nlm.nih.gov/pubmed/18288251
http://dx.doi.org/10.1155/2007/57513
Descripción
Sumario:Nasopharyngeal carcinoma (NPC) is a rare malignancy in most parts of the world, but is one of the most common cancers in Southeast Asia. Both genetic and environmental factors contribute to the tumorigenesis of NPC, most notably the consumption of certain salted food items and Epstein-Barr virus infection. This review will focus on the current progress of the genetic analysis of NPC (genetic susceptibilities and somatic alterations). We will review the current advances in genomic technologies and their shaping of the future direction of NPC research.

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