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DNMT1 interacts with the developmental transcriptional repressor HESX1
Hesx1 is a highly conserved homeobox gene present in vertebrates, but absent from invertebrates. Gene targeting experiments in mice have shown that this transcriptional repressor is required for normal forebrain and pituitary development. In humans, mutations in HESX1 impairing either its repressing...
Autores principales: | Sajedi, Ezat, Gaston-Massuet, Carles, Andoniadou, Cynthia L., Signore, Massimo, Hurd, Paul J., Dattani, Mehul, Martinez-Barbera, Juan Pedro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Pub. Co
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233781/ https://www.ncbi.nlm.nih.gov/pubmed/17931718 http://dx.doi.org/10.1016/j.bbamcr.2007.08.010 |
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