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Activating Effect of Benzbromarone, a Uricosuric Drug, on Peroxisome Proliferator-Activated Receptors

Benzbromarone, a uricosuric drug, reportedly causes hepatic hypertrophy accompanied by proliferation of peroxisomes in rats. To elucidate the mechanisms underlying induction of peroxisome proliferation by benzbromarone, we examined binding affinity for peroxisome proliferator-activated receptor [For...

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Detalles Bibliográficos
Autores principales:	Kunishima, Chiyoko, Inoue, Ikuo, Oikawa, Toshihiro, Nakajima, Hiromu, Komoda, Tsugikazu, Katayama, Shigehiro
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233808/ https://www.ncbi.nlm.nih.gov/pubmed/18274627 http://dx.doi.org/10.1155/2007/36092

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