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Openings of the Rat Recombinant α1 Homomeric Glycine Receptor as a Function of the Number of Agonist Molecules Bound
The functional properties of rat homomeric α1 glycine receptors were investigated using whole-cell and outside-out recording from human embryonic kidney cells transfected with rat α1 subunit cDNA. Whole-cell dose-response curves gave EC (50) estimates between 30 and 120 μM and a Hill slope of ∼3.3....
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2002
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233816/ https://www.ncbi.nlm.nih.gov/pubmed/11981023 http://dx.doi.org/10.1085/jgp.20028530 |