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The Relationship between Camp, Ca(2)+, and Transport of Cftr to the Plasma Membrane
The mechanism whereby cAMP stimulates Cl(−) flux through CFTR ion channels in secretory epithelia remains controversial. It is generally accepted that phosphorylation by cAMP-dependent protein kinase increases the open probability of the CFTR channel. A more controversial hypothesis is that cAMP tri...
Autores principales: | Chen, Peng, Hwang, Tzyh-Chang, Gillis, Kevin D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233831/ https://www.ncbi.nlm.nih.gov/pubmed/11479341 |
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