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The Relationship between Camp, Ca(2)+, and Transport of Cftr to the Plasma Membrane

The mechanism whereby cAMP stimulates Cl(−) flux through CFTR ion channels in secretory epithelia remains controversial. It is generally accepted that phosphorylation by cAMP-dependent protein kinase increases the open probability of the CFTR channel. A more controversial hypothesis is that cAMP tri...

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Detalles Bibliográficos
Autores principales: Chen, Peng, Hwang, Tzyh-Chang, Gillis, Kevin D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233831/
https://www.ncbi.nlm.nih.gov/pubmed/11479341

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