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Voltage-Controlled Gating at the Intracellular Entrance to a Hyperpolarization-Activated Cation Channel

Hyperpolarization-activated cation (HCN) channels regulate pacemaking activity in cardiac cells and neurons. Our previous work using the specific HCN channel blocker ZD7288 provided evidence for an intracellular activation gate for these channels because it appears that ZD7288, applied from the intr...

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Detalles Bibliográficos
Autores principales:	Rothberg, Brad S., Shin, Ki Soon, Phale, Prashant S., Yellen, Gary
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2002
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2233860/ https://www.ncbi.nlm.nih.gov/pubmed/11773240

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