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Phosphorylation of Titin Modulates Passive Stiffness of Cardiac Muscle in a Titin Isoform-dependent Manner

We investigated the effect of protein kinase A (PKA) on passive force in skinned cardiac tissues that express different isoforms of titin, i.e., stiff (N2B) and more compliant (N2BA) titins, at different levels. We used rat ventricular (RV), bovine left ventricular (BLV), and bovine left atrial (BLA...

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Detalles Bibliográficos
Autores principales:	Fukuda, Norio, Wu, Yiming, Nair, Preetha, Granzier, Henk L.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2005
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234012/ https://www.ncbi.nlm.nih.gov/pubmed/15738048 http://dx.doi.org/10.1085/jgp.200409177

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