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A Highly Ca(2+)-sensitive Pool of Granules Is Regulated by Glucose and Protein Kinases in Insulin-secreting INS-1 Cells

We have used membrane capacitance measurements and carbon-fiber amperometry to assay exocytosis triggered by photorelease of caged Ca(2+) to directly measure the Ca(2+) sensitivity of exocytosis from the INS-1 insulin-secreting cell line. We find heterogeneity of the Ca(2+) sensitivity of release in...

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Detalles Bibliográficos
Autores principales: Yang, Yan, Gillis, Kevin D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234025/
https://www.ncbi.nlm.nih.gov/pubmed/15572344
http://dx.doi.org/10.1085/jgp.200409081

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