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Akt regulates centrosome migration and spindle orientation in the early Drosophila melanogaster embryo

Correct positioning and morphology of the mitotic spindle is achieved through regulating the interaction between microtubules (MTs) and cortical actin. Here we find that, in the Drosophila melanogaster early embryo, reduced levels of the protein kinase Akt result in incomplete centrosome migration a...

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Detalles Bibliográficos
Autores principales:	Buttrick, Graham J., Beaumont, Luke M.A., Leitch, Jessica, Yau, Christopher, Hughes, Julian R., Wakefield, James G.
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234228/ https://www.ncbi.nlm.nih.gov/pubmed/18268102 http://dx.doi.org/10.1083/jcb.200705085

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