Cripto promotes A–P axis specification independently of its stimulatory effect on Nodal autoinduction

The EGF-CFC gene cripto governs anterior–posterior (A–P) axis specification in the vertebrate embryo. Existing models suggest that Cripto facilitates binding of Nodal to an ActRII–activin-like kinase (ALK) 4 receptor complex. Cripto also has a crucial function in cellular transformation that is inde...

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Detalles Bibliográficos
Autores principales: D'Andrea, Daniela, Liguori, Giovanna L., Le Good, J. Ann, Lonardo, Enza, Andersson, Olov, Constam, Daniel B., Persico, Maria G., Minchiotti, Gabriella
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234230/
https://www.ncbi.nlm.nih.gov/pubmed/18268105
http://dx.doi.org/10.1083/jcb.200709090

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