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Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint

The mitotic checkpoint is an essential surveillance mechanism that ensures high fidelity chromosome segregation during mitosis. Mitotic checkpoint function depends on numerous kinetochore proteins, including ZW10, ROD, and Zwilch (the ROD–ZW10–Zwilch complex). Through an extensive mutagenesis screen...

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Detalles Bibliográficos
Autores principales: Famulski, Jakub K., Vos, Larissa, Sun, Xuejun, Chan, Gordon
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234252/
https://www.ncbi.nlm.nih.gov/pubmed/18268100
http://dx.doi.org/10.1083/jcb.200708021