Cargando…

Long-lived virus-reactive memory T cells generated from purified cytokine-secreting T helper type 1 and type 2 effectors

Many vaccination strategies and immune cell therapies aim at increasing the numbers of memory T cells reactive to protective antigens. However, the differentiation lineage and therefore the optimal generation conditions of CD4 memory cells remain controversial. Linear and divergent differentiation m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Löhning, Max, Hegazy, Ahmed N., Pinschewer, Daniel D., Busse, Dorothea, Lang, Karl S., Höfer, Thomas, Radbruch, Andreas, Zinkernagel, Rolf M., Hengartner, Hans
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234365/ https://www.ncbi.nlm.nih.gov/pubmed/18195073 http://dx.doi.org/10.1084/jem.20071855

Ejemplares similares

An Instructive Component in T Helper Cell Type 2 (Th2) Development Mediated by Gata-3
por: Farrar, J. David, et al.
Publicado: (2001)

GATA-3 in Human T Cell Helper Type 2 Development
por: Skapenko, Alla, et al.
Publicado: (2004)

Instruction for Cytokine Expression in T Helper Lymphocytes in Relation to Proliferation and Cell Cycle Progression
por: Richter, Anne, et al.
Publicado: (1999)

“Negative Vaccination” by Specific CD4(+) T Cell Tolerisation Enhances Virus-Specific Protective Antibody Responses
por: Lang, Karl S., et al.
Publicado: (2007)

Cd4(+) T Cell Subsets during Virus Infection: Protective Capacity Depends on Effector Cytokine Secretion and on Migratory Capability
por: Maloy, Kevin J., et al.
Publicado: (2000)

The Absence of Interleukin 1 Receptor–Related T1/St2 Does Not Affect T Helper Cell Type 2 Development and Its Effector Function
por: Hoshino, Katsuaki, et al.
Publicado: (1999)

Induction of Protective Cytotoxic T Cell Responses in the Presence of High Titers of Virus-neutralizing Antibodies: Implications for Passive and Active Immunization
por: Seiler, Peter, et al.
Publicado: (1998)

CD49b/CD69-Dependent Generation of Resting T Helper Cell Memory
por: Hanazawa, Asami, et al.
Publicado: (2013)

Differential Expression of Chemokine Receptors and Chemotactic Responsiveness of Type 1 T Helper Cells (Th1s) and Th2s
por: Bonecchi, Raffaella, et al.
Publicado: (1998)

Mechanism of Transforming Growth Factor β–induced Inhibition of T Helper Type 1 Differentiation
por: Gorelik, Leonid, et al.
Publicado: (2002)

Human Nerve Growth Factor Protects Common Marmosets against Autoimmune Encephalomyelitis by Switching the Balance of T Helper Cell Type 1 and 2 Cytokines within the Central Nervous System
por: Villoslada, Pablo, et al.
Publicado: (2000)

Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals
por: Villarino, Alejandro V., et al.
Publicado: (2007)

Critical Contribution of Ox40 Ligand to T Helper Cell Type 2 Differentiation in Experimental Leishmaniasis
por: Akiba, Hisaya, et al.
Publicado: (2000)

Two Subsets of Naive T Helper Cells with Distinct T Cell Receptor Excision Circle Content in Human Adult Peripheral Blood
por: Kimmig, Sonja, et al.
Publicado: (2002)

Follicular dendritic cells control engulfment of apoptotic bodies by secreting Mfge8
por: Kranich, Jan, et al.
Publicado: (2008)

Complementary and Alternative Medicine in Children with Type 1 Diabetes Mellitus
por: Haliloglu, Belma, et al.
Publicado: (2011)

Inflammatory Cytokine Profiles During Exercise in Obese, Diabetic, and Healthy Children
por: Galassetti, Pietro R., et al.
Publicado: (2011)

A Signal Transducer and Activator of Transcription (Stat)4-independent Pathway for the Development of T Helper Type 1 Cells
por: Kaplan, Mark H., et al.
Publicado: (1998)

Repression of interleukin-4 in T helper type 1 cells by Runx/Cbfβ binding to the Il4 silencer
por: Naoe, Yoshinori, et al.
Publicado: (2007)

Lipopolysaccharide-enhanced, Toll-like Receptor 4–dependent T Helper Cell Type 2 Responses to Inhaled Antigen
por: Eisenbarth, Stephanie C., et al.
Publicado: (2002)

Expression of ICOS In Vivo Defines CD4(+) Effector T Cells with High Inflammatory Potential and a Strong Bias for Secretion of Interleukin 10
por: Löhning, Max, et al.
Publicado: (2003)

Primary Role for GI Protein Signaling in the Regulation of Interleukin 12 Production and the Induction of T Helper Cell Type 1 Responses
por: He, Jianping, et al.
Publicado: (2000)

Anti–Interleukin 10 Receptor Monoclonal Antibody Is an Adjuvant for T Helper Cell Type 1 Responses to Soluble Antigen Only in the Presence of Lipopolysaccharide
por: Castro, Antonio G., et al.
Publicado: (2000)

T1/St2-Deficient Mice Demonstrate the Importance of T1/St2 in Developing Primary T Helper Cell Type 2 Responses
por: Townsend, Michael J., et al.
Publicado: (2000)

Aplastic Anemia Rescued by Exhaustion of Cytokine-secreting CD8(+) T Cells in Persistent Infection with Lymphocytic Choriomeningitis Virus
por: Binder, Daniel, et al.
Publicado: (1998)

Dissecting the dynamic transcriptional landscape of early T helper cell differentiation into Th1, Th2, and Th1/2 hybrid cells
por: Burt, Philipp, et al.
Publicado: (2022)

Prostaglandin D2 Selectively Induces Chemotaxis in T Helper Type 2 Cells, Eosinophils, and Basophils via Seven-Transmembrane Receptor Crth2
por: Hirai, Hiroyuki, et al.
Publicado: (2001)

Protective T Cell–Independent Antiviral Antibody Responses Are Dependent on Complement
por: Ochsenbein, Adrian F., et al.
Publicado: (1999)

Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines
por: Nolting, Jens, et al.
Publicado: (2009)

P-Selectin Glycoprotein Ligand-1 (PSGL-1) on T Helper 1 but Not on T Helper 2 Cells Binds to P-Selectin and Supports Migration into Inflamed Skin
por: Borges, Eric, et al.
Publicado: (1997)

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract
por: Owyang, Alexander M., et al.
Publicado: (2006)

Efficient Interaction of HIV-1 with Purified Dendritic Cells via Multiple Chemokine Coreceptors
por: Granelli-Piperno, Angela, et al.
Publicado: (1996)

Granulocyte/macrophage colony-stimulating factor and accessory cells modulate radioprotection by purified hematopoietic cells
por: Katsumoto, Tamiko R., et al.
Publicado: (2005)

Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b
por: Föger, Niko, et al.
Publicado: (2011)

Determinant Spreading of T Helper Cell 2 (Th2) Responses to Pancreatic Islet Autoantigens
por: Tian, Jide, et al.
Publicado: (1997)

T follicular helper cells differentiate from Th2 cells in response to helminth antigens
por: Zaretsky, Arielle Glatman, et al.
Publicado: (2009)

Cytokines induce effector T-helper cells during invasive aspergillosis; what we have learned about T-helper cells?
por: Thakur, Raman, et al.
Publicado: (2015)

CYTOTOXIC THYMUS-DERIVED LYMPHOCYTES IN CEREBROSPINAL FLUID OF MICE WITH LYMPHOCYTIC CHORIOMENINGITIS
por: Zinkernagel, R. M., et al.
Publicado: (1973)

Yersinia type III secretion: send in the effectors
por: Cornelis, Guy R.
Publicado: (2002)

Suppression of type III effector secretion by polymers
por: Ohgita, Takashi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_27hbu2stl4ulg4nm5nq64ekf5v