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Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs
The onset of the adaptive immune response to Mycobacterium tuberculosis is delayed compared with that of other infections or immunization, and allows the bacterial population in the lungs to expand markedly during the preimmune phase of infection. We used adoptive transfer of M. tuberculosis Ag85B-s...
Autores principales: | Wolf, Andrea J., Desvignes, Ludovic, Linas, Beth, Banaiee, Niaz, Tamura, Toshiki, Takatsu, Kiyoshi, Ernst, Joel D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234384/ https://www.ncbi.nlm.nih.gov/pubmed/18158321 http://dx.doi.org/10.1084/jem.20071367 |
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