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The presence of β(2)-adrenoceptors sensitizes α(2A)-adrenoceptors to desensitization after chronic epinephrine treatment

BACKGROUND: In addition to the regulation of blood pressure, α(2)- and β-adrenoceptor (AR) subtypes play an important role in the modulation of noradrenergic neurotransmission in the human CNS and PNS. Several studies suggest that the α(2)-AR responsiveness in cells and tissues after chronic epineph...

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Detalles Bibliográficos
Autores principales: Bawa-Khalfe, Tasneem, Altememi, Ghazi F, Mandyam, Chitra D, Schwarz, Lindsay A, Eikenburg, Douglas C, Standifer, Kelly M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234403/
https://www.ncbi.nlm.nih.gov/pubmed/18096057
http://dx.doi.org/10.1186/1471-2210-7-16