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The presence of β(2)-adrenoceptors sensitizes α(2A)-adrenoceptors to desensitization after chronic epinephrine treatment
BACKGROUND: In addition to the regulation of blood pressure, α(2)- and β-adrenoceptor (AR) subtypes play an important role in the modulation of noradrenergic neurotransmission in the human CNS and PNS. Several studies suggest that the α(2)-AR responsiveness in cells and tissues after chronic epineph...
Autores principales: | Bawa-Khalfe, Tasneem, Altememi, Ghazi F, Mandyam, Chitra D, Schwarz, Lindsay A, Eikenburg, Douglas C, Standifer, Kelly M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234403/ https://www.ncbi.nlm.nih.gov/pubmed/18096057 http://dx.doi.org/10.1186/1471-2210-7-16 |
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