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Effect of Na(+) Flow on Cd(2+) Block of Tetrodotoxin-resistant Na(+) Channels
Tetrodotoxin-resistant (TTX-R) Na(+) channels are 1,000-fold less sensitive to TTX than TTX-sensitive (TTX-S) Na(+) channels. On the other hand, TTX-R channels are much more susceptible to external Cd(2+) block than TTX-S channels. A cysteine (or serine) residue situated just next to the aspartate r...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2002
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234463/ https://www.ncbi.nlm.nih.gov/pubmed/12149278 http://dx.doi.org/10.1085/jgp.20018536 |