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Activation of the neurokinin-1 receptor by substance P triggers the release of substance P from cultured adult rat dorsal root ganglion neurons

BACKGROUND: Although substance P (SP) is an important primary afferent modulator in nociceptive processes, it is unclear whether SP regulates its own release from primary sensory neurons. RESULTS: Using a highly sensitive radioimmunoassay for SP, we have demonstrated that the activation of neurokini...

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Detalles Bibliográficos
Autores principales: Tang, He-Bin, Li, Yu-Sang, Arihiro, Koji, Nakata, Yoshihiro
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2235838/
https://www.ncbi.nlm.nih.gov/pubmed/18157919
http://dx.doi.org/10.1186/1744-8069-3-42