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Reactive oxygen species and p47phox activation are essential for the Mycobacterium tuberculosis-induced pro-inflammatory response in murine microglia

BACKGROUND: Activated microglia elicits a robust amount of pro-inflammatory cytokines, which are implicated in the pathogenesis of tuberculosis in the central nervous system (CNS). However, little is known about the intracellular signaling mechanisms governing these inflammatory responses in microgl...

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Detalles Bibliográficos
Autores principales: Yang, Chul-Su, Lee, Hye-Mi, Lee, Ji-Yeon, Kim, Jeong-Ah, Lee, Sung Joong, Shin, Dong-Min, Lee, Young-Ho, Lee, Dong-Seok, El-Benna, Jamel, Jo, Eun-Kyeong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2235845/
https://www.ncbi.nlm.nih.gov/pubmed/18036262
http://dx.doi.org/10.1186/1742-2094-4-27

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