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Loss of Cytokine-STAT5 Signaling in the CNS and Pituitary Gland Alters Energy Balance and Leads to Obesity

Signal transducers and activators of transcription (STATs) are critical components of cytokine signaling pathways. STAT5A and STAT5B (STAT5), the most promiscuous members of this family, are highly expressed in specific populations of hypothalamic neurons in regions known to mediate the actions of c...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Yeon, Muenzberg, Heike, Gavrilova, Oksana, Reed, Jacquelyn A., Berryman, Darlene, Villanueva, Eneida C., Louis, Gwendolyn W., Leinninger, Gina M., Bertuzzi, Stefano, Seeley, Randy J., Robinson, Gertraud W., Myers, Martin G., Hennighausen, Lothar
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237899/
https://www.ncbi.nlm.nih.gov/pubmed/18286195
http://dx.doi.org/10.1371/journal.pone.0001639