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Loss of Cytokine-STAT5 Signaling in the CNS and Pituitary Gland Alters Energy Balance and Leads to Obesity
Signal transducers and activators of transcription (STATs) are critical components of cytokine signaling pathways. STAT5A and STAT5B (STAT5), the most promiscuous members of this family, are highly expressed in specific populations of hypothalamic neurons in regions known to mediate the actions of c...
Autores principales: | Lee, Ji-Yeon, Muenzberg, Heike, Gavrilova, Oksana, Reed, Jacquelyn A., Berryman, Darlene, Villanueva, Eneida C., Louis, Gwendolyn W., Leinninger, Gina M., Bertuzzi, Stefano, Seeley, Randy J., Robinson, Gertraud W., Myers, Martin G., Hennighausen, Lothar |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237899/ https://www.ncbi.nlm.nih.gov/pubmed/18286195 http://dx.doi.org/10.1371/journal.pone.0001639 |
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