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THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM

1. The electrophoretic activity of particles of human skin in distilled water and different concentrations of salt solutions has been studied. The electrokinetic potential and the charge density were determined and comparisons made with results obtained by electroendosmosis. 2. The electrokinetic po...

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Autor principal: Wilkerson, Vernon A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1939
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237920/
https://www.ncbi.nlm.nih.gov/pubmed/19873144
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author Wilkerson, Vernon A.
author_facet Wilkerson, Vernon A.
author_sort Wilkerson, Vernon A.
collection PubMed
description 1. The electrophoretic activity of particles of human skin in distilled water and different concentrations of salt solutions has been studied. The electrokinetic potential and the charge density were determined and comparisons made with results obtained by electroendosmosis. 2. The electrokinetic potential is ultimately decreased if sufficient salt is added. The order of inhibition is Al > Ca > Ba > K > Na. 3. The lyotrophic series Li > Na > K > Rb and Cl > I > Br express respectively the comparative effect of the monovalent cations and anions upon the electrokinetic potential of the skin. 4. Since both electrophoresis and electroendosmosis are dependent upon the electrokinetic potential, it follows from the results obtained, that the greatest rate of flow through the human skin under the force of an applied electrical current would be given by concentrations of neutral salts between 0.0001 M and 0.0002 M.
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spelling pubmed-22379202008-04-23 THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM Wilkerson, Vernon A. J Gen Physiol Article 1. The electrophoretic activity of particles of human skin in distilled water and different concentrations of salt solutions has been studied. The electrokinetic potential and the charge density were determined and comparisons made with results obtained by electroendosmosis. 2. The electrokinetic potential is ultimately decreased if sufficient salt is added. The order of inhibition is Al > Ca > Ba > K > Na. 3. The lyotrophic series Li > Na > K > Rb and Cl > I > Br express respectively the comparative effect of the monovalent cations and anions upon the electrokinetic potential of the skin. 4. Since both electrophoresis and electroendosmosis are dependent upon the electrokinetic potential, it follows from the results obtained, that the greatest rate of flow through the human skin under the force of an applied electrical current would be given by concentrations of neutral salts between 0.0001 M and 0.0002 M. The Rockefeller University Press 1939-11-20 /pmc/articles/PMC2237920/ /pubmed/19873144 Text en Copyright © Copyright, 1939, The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Wilkerson, Vernon A.
THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM
title THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM
title_full THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM
title_fullStr THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM
title_full_unstemmed THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM
title_short THE CHEMISTRY OF HUMAN SKIN : IV. THE ELECTROKINETIC EFFECT OF VARIOUS IONS UPON SUSPENDED PARTICLES OF STRATUM CORNEUM
title_sort chemistry of human skin : iv. the electrokinetic effect of various ions upon suspended particles of stratum corneum
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237920/
https://www.ncbi.nlm.nih.gov/pubmed/19873144
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