STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS

The isolated Ringer-perfused frog liver is able to concentrate in its secretion several hundred or even thousand times a great number of dyestuffs. When two dyestuffs are perfused simultaneously, the liver separates them to a lower or higher degree, some times to such an extent that the secretion of...

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Detalles Bibliográficos
Autor principal: Hober, Rudolf
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1939
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237924/
https://www.ncbi.nlm.nih.gov/pubmed/19873147
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author Hober, Rudolf
author_facet Hober, Rudolf
author_sort Hober, Rudolf
collection PubMed
description The isolated Ringer-perfused frog liver is able to concentrate in its secretion several hundred or even thousand times a great number of dyestuffs. When two dyestuffs are perfused simultaneously, the liver separates them to a lower or higher degree, some times to such an extent that the secretion of one of them is entirely suppressed by the other. Which one of the two dyestuffs appears prevailingly in the secretion, does not depend upon its diffusibility or lipoid solubility, but perhaps upon its adsorbability. This is concluded from the fact that dyestuffs provided with several (4 to 5) strongly hydrophilic sulfonate groups in their molecule, are not permitted to pass the gland.
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spelling pubmed-22379242008-04-23 STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS Hober, Rudolf J Gen Physiol Article The isolated Ringer-perfused frog liver is able to concentrate in its secretion several hundred or even thousand times a great number of dyestuffs. When two dyestuffs are perfused simultaneously, the liver separates them to a lower or higher degree, some times to such an extent that the secretion of one of them is entirely suppressed by the other. Which one of the two dyestuffs appears prevailingly in the secretion, does not depend upon its diffusibility or lipoid solubility, but perhaps upon its adsorbability. This is concluded from the fact that dyestuffs provided with several (4 to 5) strongly hydrophilic sulfonate groups in their molecule, are not permitted to pass the gland. The Rockefeller University Press 1939-11-20 /pmc/articles/PMC2237924/ /pubmed/19873147 Text en Copyright © Copyright, 1939, The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Hober, Rudolf
STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS
title STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS
title_full STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS
title_fullStr STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS
title_full_unstemmed STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS
title_short STUDIES CONCERNING THE NATURE OF THE SECRETORY ACTIVITY OF THE ISOLATED RINGER-PERFUSED FROG LIVER : I. THE DIFFERENTIAL SECRETION OF PAIRS OF DYESTUFFS
title_sort studies concerning the nature of the secretory activity of the isolated ringer-perfused frog liver : i. the differential secretion of pairs of dyestuffs
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237924/
https://www.ncbi.nlm.nih.gov/pubmed/19873147
work_keys_str_mv AT hoberrudolf studiesconcerningthenatureofthesecretoryactivityoftheisolatedringerperfusedfrogliverithedifferentialsecretionofpairsofdyestuffs

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