ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST

1. The adsorption rate constant of phage to bacterium is found to change between wide limits, depending on the physiological state of the bacterium. 2. The experiments of Krueger and of Schlesinger on the residual free phage in contact with an excess of bacteria are discussed and the view of Schlesi...

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Detalles Bibliográficos
Autor principal: Delbrück, M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237952/
https://www.ncbi.nlm.nih.gov/pubmed/19873179
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author Delbrück, M.
author_facet Delbrück, M.
author_sort Delbrück, M.
collection PubMed
description 1. The adsorption rate constant of phage to bacterium is found to change between wide limits, depending on the physiological state of the bacterium. 2. The experiments of Krueger and of Schlesinger on the residual free phage in contact with an excess of bacteria are discussed and the view of Schlesinger, that they represent phage particles with reduced affinity to the bacterial host is supported by experiments. 3. The theory of von Smoluchowski and Schlesinger is compared with the experiments. 4. The implications of these findings for the assay methods currently used are discussed.
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spelling pubmed-22379522008-04-23 ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST Delbrück, M. J Gen Physiol Article 1. The adsorption rate constant of phage to bacterium is found to change between wide limits, depending on the physiological state of the bacterium. 2. The experiments of Krueger and of Schlesinger on the residual free phage in contact with an excess of bacteria are discussed and the view of Schlesinger, that they represent phage particles with reduced affinity to the bacterial host is supported by experiments. 3. The theory of von Smoluchowski and Schlesinger is compared with the experiments. 4. The implications of these findings for the assay methods currently used are discussed. The Rockefeller University Press 1940-05-20 /pmc/articles/PMC2237952/ /pubmed/19873179 Text en Copyright © Copyright, 1940, The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Delbrück, M.
ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST
title ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST
title_full ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST
title_fullStr ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST
title_full_unstemmed ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST
title_short ADSORPTION OF BACTERIOPHAGE UNDER VARIOUS PHYSIOLOGICAL CONDITIONS OF THE HOST
title_sort adsorption of bacteriophage under various physiological conditions of the host
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237952/
https://www.ncbi.nlm.nih.gov/pubmed/19873179
work_keys_str_mv AT delbruckm adsorptionofbacteriophageundervariousphysiologicalconditionsofthehost

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